Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
FN5 Cmp-3f(a)-neu5ac
Code : 3S44
Header : TRANSFERASE
Title : Crystal Structure of Pasteurella multocida sialyltransferase M144D mutant with CMP bound
Release Data : 2012-08-15
Compound :
mol_id molecule chains
1 Alpha-2,3/2,6-sialyltransferase/sialidase A
ec: 2.4.99.-
fragment: UNP residues 26-412
mutation: M144D
Source :
mol_id organism_scientific expression_system
1 Pasteurella multocida  (taxid:747) Escherichia coli  (taxid:469008)
strain: P-1059
gene: homologue of Pm0188
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET23a(+)
Authors : Sugiarto, G., Lau, K., Li, Y., Lim, S., Ames, J.B., Le, D.-T., Fisher, A.J., Chen, X.
Keywords : GT-B fold, Sialyltransferase, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.45 Å )
Citation :

A Sialyltransferase Mutant with Decreased Donor Hydrolysis and Reduced Sialidase Activities for Directly Sialylating Lewis(x).

Sugiarto, G.,Lau, K.,Qu, J.  et al.
(2012)  Acs Chem.Biol.  7 : 1232 - 1240

PubMed: 22583967
DOI: 10.1021/cb300125k

Chain : A
UniProt : Q15KI8 (No found in current UniProtKB/SwissProt)
Reaction : -