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Ligands
Code Name Style Show Link
FMP Formycin-5'-monophosphate
BGC Beta-D-glucopyranose
GAL Beta-D-galactopyranose
: Polysaccharide
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
Code Name Show
Code : 3RTI   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Crystal structure of ricin bound with formycin monophosphate
Release Data : 2011-08-31
Compound :
mol_id molecule chains synonym
1 Ricin A Ricin A chain, rRNA N-glycosidase, Linker peptide, Ricin B chain
ec: 3.2.2.22
fragment: Ricin A chain
mol_id molecule chains synonym
2 Ricin B Ricin A chain, rRNA N-glycosidase, Linker peptide, Ricin B chain
ec: 3.2.2.22
fragment: Ricin B chain
Source :
mol_id organism_scientific organism_common
1 Ricinus communis  (taxid:3988) Castor bean
other_details: seed
mol_id organism_scientific organism_common
2 Ricinus communis  (taxid:3988) Castor bean
other_details: seed
Authors : Monzingo, A.F., Robertus, J.D.
Keywords : glycosidase, ribosome-inactivating protein, lectin, glycoprotein, lactose binding, glycosylation, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.8 Å )
Citation :

X-ray analysis of substrate analogs in the ricin A-chain active site.

Monzingo, A.F.,Robertus, J.D.
(1992)  J.Mol.Biol.  227 : 1136 - 1145

PubMed: 1433290

Chain : B
UniProt : P02879 (RICI_RICCO)
Reaction: EC: Evidence:
Physiological Direction:
[Ricin A chain]
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
3.2.2.22 -
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