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Ligands
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SIN Succinic acid
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Code : 3RT3   PDBj   RCSB PDB   PDBe
Header : ANTIVIRAL PROTEIN/VIRAL PROTEIN
Title : Complex of influenza virus protein with host anti-viral factor
Release Data : 2011-07-13
Compound :
mol_id molecule chains synonym
1 Ubiquitin-like protein ISG15 B Interferon-induced 15 kDa protein, Interferon-induced 17 kDa protein, IP17, Ubiquitin cross-reactive protein, hUCRP
mutation: C78S
mol_id molecule chains synonym
2 Non-structural protein 1 C NS1, NS1B
fragment: N-terminal G1P2-binding domain, UNP residues 1-103
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: ISG15, G1P2, UCRP
expression_system_vector_type: plasmid
expression_system_plasmid: pGEX-6P-1
mol_id organism_scientific expression_system
2 Influenza B virus  (taxid:107412) Escherichia coli  (taxid:562)
strain: B/Lee/1940
gene: NS
expression_system_vector_type: plasmid
expression_system_plasmid: pET-22b
Authors : Wang, X.Q., Li, L.
Keywords : ubiquitin-like domain, ISGylation, ANTIVIRAL PROTEIN-VIRAL PROTEIN complex
Exp. method : X-RAY DIFFRACTION ( 2.006 Å )
Citation :

Crystal structure of human ISG15 in complex with influenza B virus NS1B

Li, L.,Wang, X.Q.
To be Published 

Chain : B
UniProt : P05161 (ISG15_HUMAN)
Reaction : -
Chain : C
UniProt : P03502 (NS1_INBLE)
Reaction : -