PDB ID: 3RQD
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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ZN | Zinc ion | PoSSuM | |||
K | Potassium ion | PoSSuM |
Code | Name | Show |
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BB9 | (2z)-2-amino-3-sulfanylprop-2-enoic acid | |
03Y | 2-methyl-L-cysteine |
Code | Name | Emphasize |
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Code | Name | Show |
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02G | (3s,4e)-3-hydroxy-7-sulfanylhept-4-enoic acid |
Download interaction data: 3RQD
Structure summary
Code : | 3RQD PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||||||||||||||
Title : | Ideal Thiolate-Zinc Coordination Geometry in Depsipeptide Binding to Histone Deacetylase 8 | ||||||||||||||||||||||||
Release Data : | 2011-08-24 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Cole, K.E., Dowling, D.P., Christianson, D.W. | ||||||||||||||||||||||||
Keywords : | histone deacetylase, largazole, histone deacetylation, HYDROLASE-HYDROLASE INHIBITOR complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.143 Å ) | ||||||||||||||||||||||||
Citation : |
Structural basis of the antiproliferative activity of largazole, a depsipeptide inhibitor of the histone deacetylases.
Cole, K.E.,Dowling, D.P.,Boone, M.A.
et al.
PubMed: 21790156 |
Reaction
Chain : | A, B | ||||||||||||||||
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UniProt : | Q9BY41 (HDAC8_HUMAN) | ||||||||||||||||
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