Het-PDB Navi2 (PDB: 3RN8)

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Ligands
Code	Name	Link
GLU	Glutamic acid	PoSSuM
RN8	3,3'-benzene-1,4-diylbis(4-cyano-5-ethylthiophene-2-carboxylic acid)	PoSSuM
ZN	Zinc ion	PoSSuM
ACT	Acetate ion	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 3RN8

Code :

3RN8 PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

Crystal Structure of iGluR2 Ligand Binding Domain and Symmetrical Carboxyl Containing Potentiator

Release Data :

2011-05-25

Compound :

mol_id	molecule	chains	synonym
1	Glutamate receptor 2	A,B,C	GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2
	fragment: UNP residues 413-527, 653-812

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: GRIA2, GLUR2

Authors :

Timm, D.E.

Keywords :

glutamate receptor potentiator complex, ligand gated ion channel, membrane, TRANSPORT PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.70 Å )

Citation :

Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation.

Timm, D.E.,Benveniste, M.,Weeks, A.M. et al.
(2011) Mol.Pharmacol. 80 : 267 - 280

PDB ID: 3RN8