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Ligands
Code Name Style Show Link
PEG Di(hydroxyethyl)ether
Non-standard Residues
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TYS O-sulfo-L-tyrosine
Glycosylation
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Code : 3Q6F   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120
Release Data : 2011-05-25
Compound :
mol_id molecule chains
1 Light chain of Fab of human mAb 2909 A,C,E,G,I,K
mol_id molecule chains
2 Heavy chain of Fab of human mAb 2909 B,D,F,H,J,L
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
mol_id organism_scientific organism_common
2 Homo sapiens  (taxid:9606) Human
Authors : Spurrier, B., Sampson, J., Totrov, M., Li, H., O'Neal, T., William, C., Robinson, J., Gorny, M.K., Zolla-Pazner, S., Kong, X.P.
Keywords : IgG, neutralization of HIV-1 viruses, Quaternary epitope of HIV-1 gp120, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 3.192 Å )
Citation :

Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.

Spurrier, B.,Sampson, J.M.,Totrov, M.  et al.
(2011)  Structure  19 : 691 - 699

PubMed: 21565703
DOI: 10.1016/j.str.2011.02.012