PDB ID: 3Q61
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Structure summary
Code : | 3Q61 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | DNA | ||||||||||||
Title : | 3'-Fluoro Hexitol Nucleic Acid DNA Structure | ||||||||||||
Release Data : | 2012-01-18 | ||||||||||||
Compound : |
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Authors : | Seth, P.R., Allerson, C.R., Prakash, T.P., Siwkowski, A., Berdeja, A., Yu, J., Pallan, P.S., Watt, A.T., Gaus, H., Bhat, B., Egli, M., Swayze, E.E. | ||||||||||||
Keywords : | A-FORM DNA, 3'-Fluoro Hexitol Nucleic Acid, FHNA, Antisense oligonucleotides, DNA | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.56 Å ) | ||||||||||||
Citation : |
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides.
Egli, M.,Pallan, P.S.,Allerson, C.R.
et al.
PubMed: 21919455 |