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Ligands
Code Name Style Show Link
CKI N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide
NI Nickel (II) ion
Non-standard Residues
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Glycosylation
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Code : 3Q2M   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE/TRANSFERASE INHIBITOR
Title : Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, Protein Kinase Inhibitor CKI-7 Complex
Release Data : 2011-05-18
Compound :
mol_id molecule chains
1 Spectinomycin phosphotransferase A
Source :
mol_id organism_scientific expression_system
1 Legionella pneumophila 130b  (taxid:866628) Escherichia coli  (taxid:562)
strain: serogroup 1 strain 130b
gene: aph, LPW_21961
expression_system_strain: BB101
expression_system_vector_type: plasmid
expression_system_plasmid: pET21b
Authors : Berghuis, A.M., Fong, D.H., Xiong, B., Hwang, J.
Keywords : Ser/Thr/Tyr protein kinase, phosphotransferase, phosphorylation, cytosol, TRANSFERASE-TRANSFERASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.90 Å )
Citation :

Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor.

Fong, D.H.,Xiong, B.,Hwang, J.  et al.
(2011)  Plos One  6 : e19589 - e19589

PubMed: 21573013
DOI: 10.1371/journal.pone.0019589

Chain : A
UniProt : E1XXQ2 (O06916_LEGPN)
Reaction : -