PDB ID: 3PP0
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Structure summary
Code : | 3PP0 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal Structure of the Kinase domain of Human HER2 (erbB2). | ||||||||||||
Release Data : | 2011-03-30 | ||||||||||||
Compound : |
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Source : |
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Authors : | Skene, R.J., Aertgeerts, K., Sogabe, S. | ||||||||||||
Keywords : | KINASE DOMAIN, ANTI-ONCOGENE, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, GLYCOPROTEIN, MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, RECEPTOR, SECRETED, TRANSFERASE, TRANSMEMBRANE, TYROSINE-PROTEIN KINASE, TYROSINE KINASE INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.25 Å ) | ||||||||||||
Citation : |
Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein.
Aertgeerts, K.,Skene, R.,Yano, J.
et al.
PubMed: 21454582 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P04626 (ERBB2_HUMAN) | ||||||||
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