PDB ID: 3PMH
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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0G7 | D-phenylalanyl-N-[(3s)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide | PoSSuM |
Code | Name | Show |
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TYS | O-sulfo-L-tyrosine |
Code | Name | Emphasize |
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MAN | Alpha-D-mannopyranose | |
NAG | 2-acetamido-2-deoxy-beta-D-glucopyranose |
Code | Name | Show |
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Download interaction data: 3PMH
Structure summary
Code : | 3PMH PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||
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Header : | blood cloting, hydrolase/inhibitor | ||||||||||||||||||||||||||||||||||||
Title : | Mechanism of Sulfotyrosine-Mediated Glycoprotein Ib Interaction with Two Distinct alpha-Thrombin Sites | ||||||||||||||||||||||||||||||||||||
Release Data : | 2011-06-01 | ||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Varughese, K.I., Celikel, R. | ||||||||||||||||||||||||||||||||||||
Keywords : | Sulfated tyrosine residues, Leucine Rich Repeats, Protease Platelet receptor of thrombin, Thrombin binding, Platelet surface, blood cloting, hydrolase-inhibitor complex | ||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.20 Å ) | ||||||||||||||||||||||||||||||||||||
Citation : |
Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I.
Zarpellon, A.,Celikel, R.,Roberts, J.R.
et al.
PubMed: 21555542 |
Reaction
Chain : | B | ||||||||
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UniProt : | P00734 (THRB_HUMAN) | ||||||||
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Chain : | G |
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UniProt : | P07359 (GP1BA_HUMAN) |
Reaction : | - |