PDB ID: 3OG7
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Structure summary
Code : | 3OG7 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | transferase/transferase inhibitor | ||||||||||||
Title : | B-Raf Kinase V600E oncogenic mutant in complex with PLX4032 | ||||||||||||
Release Data : | 2010-09-22 | ||||||||||||
Compound : |
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Source : |
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Authors : | Zhang, Y., Zhang, K.Y., Zhang, C. | ||||||||||||
Keywords : | B-Raf, BRAF, PROTO-ONCOGENE, V600E, Kinase, TRANSFERASE, transferase-transferase inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.4500 Å ) | ||||||||||||
Citation : |
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
Bollag, G.,Hirth, P.,Tsai, J.
et al.
PubMed: 20823850 |
Reaction
Chain : | A, B |
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UniProt : | Q5IBP5 (Q5IBP5_HUMAN) |
Reaction : | - |