Het-PDB Navi2 (PDB: 3NSQ)

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Ligands
Code	Name		Style	Show	Link
CHZ	1,8-dihydroxyanthracene-9,10-dione				PoSSuM

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Download interaction data: 3NSQ

Code :

3NSQ PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Crystal structure of tetrameric RXRalpha-LBD complexed with antagonist danthron

Release Data :

2010-11-17

Compound :

mol_id	molecule	chains	synonym
1	Retinoid X receptor, alpha	A,B	Retinoid X receptor, alpha, isoform CRA_b
	fragment: ligand binding domain

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: RXRA, NR2B1, RP11-473E2.1-002, hCG_18150

Authors :

Zhang, H., Hu, T., Li, L., Zhou, R., Chen, L., Hu, L., Jiang, H., Shen, X.

Keywords :

nuclear receptor retinoic x recepor alpha ligand binding domain antagonist danthron, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 2.60 Å )

Citation :

Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.

Zhang, H.,Zhou, R.,Li, L. et al.
(2011) J.Biol.Chem. 286 : 1868 - 1875

PDB ID: 3NSQ