Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CHZ 1,8-dihydroxyanthracene-9,10-dione
Code : 3NSQ
Header : TRANSCRIPTION
Title : Crystal structure of tetrameric RXRalpha-LBD complexed with antagonist danthron
Release Data : 2010-11-17
Compound :
mol_id molecule chains synonym
1 Retinoid X receptor, alpha A,B Retinoid X receptor, alpha, isoform CRA_b
fragment: ligand binding domain
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: RXRA, NR2B1, RP11-473E2.1-002, hCG_18150
Authors : Zhang, H., Hu, T., Li, L., Zhou, R., Chen, L., Hu, L., Jiang, H., Shen, X.
Keywords : nuclear receptor retinoic x recepor alpha ligand binding domain antagonist danthron, TRANSCRIPTION
Exp. method : X-RAY DIFFRACTION ( 2.60 Å )
Citation :

Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.

Zhang, H.,Zhou, R.,Li, L.  et al.
(2011)  J.Biol.Chem.  286 : 1868 - 1875

PubMed: 21084305
DOI: 10.1074/jbc.M110.166215

Chain : A, B
UniProt : Q2NL52 (RXRA_HUMAN)
Reaction : -