PDB ID: 3NBP
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Structure summary
Code : | 3NBP PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSFERASE | ||||||||||||||||||||||||
Title : | HIV-1 reverse transcriptase with aminopyrimidine inhibitor 2 | ||||||||||||||||||||||||
Release Data : | 2010-08-18 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Harris, S.F., Villasenor, A.G. | ||||||||||||||||||||||||
Keywords : | HIV, RT, REVERSE TRANSCRIPTASE, TRANSFERASE RNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, TRANSFERASE | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.95 Å ) | ||||||||||||||||||||||||
Citation : |
Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses.
Kertesz, D.J.,Brotherton-Pleiss, C.,Yang, M.
et al.
PubMed: 20538456 |
Reaction
Chain : | B | ||||||||||||||||||||||||
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UniProt : | P04585 (POL_HV1H2) | ||||||||||||||||||||||||
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