Brand  (β version)

PDB ID: 3M2J

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Ligands
Code Name Style Show Link
SO4 Sulfate ion PoSSuM
F5M 5-(2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl)-2-(6-hydroxy-3-oxo-3h-xanthen-9-yl)benzoic acid PoSSuM
Non-standard Residues
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Structure summary

Code : 3M2J   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal Structure of fluorescein-labeled Class A -lactamase PenP
Release Data : 2011-03-16
Compound :
mol_id molecule chains synonym
1 Beta-lactamase A,B Penicillinase, Large exopenicillinase, Small exopenicillinase
ec: 3.5.2.6
fragment: residues 47-301
mutation: E166C
Source :
mol_id organism_scientific expression_system
1 Bacillus licheniformis  (taxid:1402) Escherichia coli  (taxid:562)
strain: 749/C
gene: penP
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pRSET
Authors : Zhao, Y.X., Leung, Y.C., Wong, W.T.
Keywords : beta-lactamase, fluorophore, biosensor, hydrolase, Antibiotic resistance, Cell membrane, Lipoprotein, Membrane, Palmitate
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

Crystal Structure of fluorescein-labeled Class A -lactamase PenP

Zhao, Y.X.,Leung, Y.C.,Wong, W.T.
To be Published 

Reaction

Chain : A, B
UniProt : P00808 (BLAC_BACLI)
Reaction: EC: Evidence:
Physiological Direction:
a beta-lactam + H2O = a substituted beta-amino acid 3.5.2.6 PROSITE-ProRule:PRU10101
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