PDB ID: 3L13
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Structure summary
Code : | 3L13 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal Structures of Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors | ||||||||||||
Release Data : | 2010-02-16 | ||||||||||||
Compound : |
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Source : |
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Authors : | Murray, J.M., Wiesmann, C. | ||||||||||||
Keywords : | kinase, ATP-binding, Nucleotide-binding, Transferase, PI3K-gamma p110 gamma | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.000 Å ) | ||||||||||||
Citation : |
Discovery of (Thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally Available Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors for the Treatment of Cancer.
Sutherlin, D.P.,Sampath, D.,Berry, M.
et al.
PubMed: 20050669 |
Reaction
Chain : | A | |||||||||||||||||||||||
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UniProt : | P48736 (PK3CG_HUMAN) | |||||||||||||||||||||||
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