PDB ID: 3I6R
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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FMN | Flavin mononucleotide | PoSSuM | |||
J5Z | 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine | PoSSuM | |||
ORO | Orotic acid | PoSSuM |
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Download interaction data: 3I6R
Structure summary
Code : | 3I6R PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM74 | ||||||||||||
Release Data : | 2009-07-28 | ||||||||||||
Compound : |
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Source : |
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Authors : | Deng, X., Phillips, M.A. | ||||||||||||
Keywords : | Plasmodium falciparum, dihydroorotate dehydrogenase, triazolopyrimidine, inhibitor, DSM74, FAD, Flavoprotein, Membrane, Mitochondrion, Mitochondrion inner membrane, Oxidoreductase, Pyrimidine biosynthesis, Transit peptide | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.50 Å ) | ||||||||||||
Citation : |
Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds.
Deng, X.,Gujjar, R.,El Mazouni, F.
et al.
PubMed: 19640844 |
Reaction
Chain : | A | ||||||||
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UniProt : | Q08210 (PYRD_PLAF7) | ||||||||
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