PDB ID: 3HYG
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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ZN | Zinc ion | PoSSuM | |||
CA | Calcium ion | PoSSuM | |||
099 | (2r)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1s,2r)-2-hydroxy-2,3-dihydro-1h-inden-1-yl]butanediamide | PoSSuM |
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Download interaction data: 3HYG
Structure summary
Code : | 3HYG PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound | ||||||||||||
Release Data : | 2009-07-07 | ||||||||||||
Compound : |
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Source : |
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Authors : | Shieh, H.-S., Williams, J.M., Caspers, N., Mathis, K.J., Tortorella, M.D., Tomasselli, A. | ||||||||||||
Keywords : | alpha/beta structure, central five stranded beta-sheet, Cleavage on pair of basic residues, Disulfide bond, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Secreted, Zinc, Zymogen | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.40 Å ) | ||||||||||||
Citation : |
Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors
Tortorella, M.D.,Tomasselli, A.G.,Mathis, K.J.
et al.
PubMed: 19586907 |
Reaction
Chain : | A, B |
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UniProt : | Q9UNA0 (ATS5_HUMAN) |
Reaction : | - |