Het-PDB Navi2 (PDB: 3G35)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
F13	3-fluoro-N-[3-(1h-tetrazol-5-yl)phenyl]benzamide				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 3G35

Code :

3G35 PDBj RCSB PDB PDBe

Header :

HYDROLASE/HYDROLASE INHIBITOR

Title :

CTX-M-9 class A beta-lactamase complexed with compound 12 (F13)

Release Data :

2009-03-24

Compound :

mol_id	molecule	chains	synonym
1	Beta-lactamase CTX-M-9a	A,B	Beta-lactamase, CTX-M-9 beta-lactamase, Betalactamase CTX-M-9
	ec: 3.5.2.6 fragment: sequence database residues 29-291

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:562)	Escherichia coli (taxid:562)
	gene: blaCTX-M-9, blaCTX-M-9a, CTX-M expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: PET-9a

Authors :

Chen, Y., Shoichet, B.K.

Keywords :

CTX-M, beta-lactamase, molecular docking, fragment, inhibitor, Antibiotic resistance, Hydrolase, Plasmid, HYDROLASE-HYDROLASE INHIBITOR COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 1.410 Å )

Citation :

Molecular docking and ligand specificity in fragment-based inhibitor discovery

Chen, Y.,Shoichet, B.K.
(2009) Nat.Chem.Biol. 5 : 358 - 364

Chain :

A, B

UniProt :

Q9L5C8 (Q9L5C8_ECOLX)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
a beta-lactam + H2O = a substituted beta-amino acid	3.5.2.6	ARBA:ARBA00001526, RuleBase:RU361140
a beta-lactam + H2O = a substituted beta-amino acid	-	ARBA:ARBA00001526, RuleBase:RU361140

PDB ID: 3G35