Brand  (β version)

PDB ID: 3FXW

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Color scheme of protein:

Code Name Style Show Link
F10 2-[2-(2-fluorophenyl)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-C]pyridin-4-one PoSSuM

Select hetatm:   

Select hetatm:   

Select chain:  

Data format:   

Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 3FXW   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : High resolution crystal structure of mitogen-activated protein kinase-activated protein kinase 3/inhibitor 2 complex
Release Data : 2010-01-26
Compound :
mol_id molecule chains synonym
1 MAP kinase-activated protein kinase 3 A MK3, MAPK-activated protein kinase 3, MAPKAP kinase 3, MAPKAPK-3, Chromosome 3p kinase, 3pK
ec: 2.7.11.1
fragment: Kinase domain, UNP residues 33-349
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
expression_system_strain: Rosetta2
expression_system_vector_type: vector
expression_system_vector: Proprietary vector
Authors : Cheng, R.K.Y., Barker, J., Palan, S., Felicetti, B., Whittaker, M., Hesterkamp, T.
Keywords : Kinase domain fold, ATP-binding, Kinase, Nucleotide-binding, Nucleus, Phosphoprotein, Serine/threonine-protein kinase, Transferase
Exp. method : X-RAY DIFFRACTION ( 2.00 Å )
Citation :

High resolution crystal structure of mitogen-activated protein kinase-activated protein kinase 3/inhibitor 2 complex

Cheng, R.K.Y.,Barker, J.,Palan, S.  et al.
To be Published 

Reaction

Chain : A
UniProt : Q16644 (MAPK3_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+) 2.7.11.1 PubMed:8774846
-
L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+) 2.7.11.1 PubMed:8774846
-