Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
F10 2-[2-(2-fluorophenyl)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-C]pyridin-4-one
Code : 3FXW
Header : TRANSFERASE
Title : High resolution crystal structure of mitogen-activated protein kinase-activated protein kinase 3/inhibitor 2 complex
Release Data : 2010-01-26
Compound :
mol_id molecule chains synonym
1 MAP kinase-activated protein kinase 3 A MK3, MAPK-activated protein kinase 3, MAPKAP kinase 3, MAPKAPK-3, Chromosome 3p kinase, 3pK
ec: 2.7.11.1
fragment: Kinase domain, UNP residues 33-349
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
expression_system_strain: Rosetta2
expression_system_vector_type: vector
expression_system_vector: Proprietary vector
Authors : Cheng, R.K.Y., Barker, J., Palan, S., Felicetti, B., Whittaker, M., Hesterkamp, T.
Keywords : Kinase domain fold, ATP-binding, Kinase, Nucleotide-binding, Nucleus, Phosphoprotein, Serine/threonine-protein kinase, Transferase
Exp. method : X-RAY DIFFRACTION ( 2.00 Å )
Citation :

High resolution crystal structure of mitogen-activated protein kinase-activated protein kinase 3/inhibitor 2 complex

Cheng, R.K.Y.,Barker, J.,Palan, S.  et al.
To be Published 

Chain : A
UniProt : Q16644 (MAPK3_HUMAN)
Reaction : ATP + a protein = ADP + a phosphoprotein.