PDB ID: 3FQH
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Structure summary
Code : | 3FQH PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of spleen tyrosine kinase complexed with a 2-substituted 7-azaindole | ||||||||||||
Release Data : | 2009-03-10 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kuglstatter, A., Villasenor, A.G. | ||||||||||||
Keywords : | SYK, SPLEEN TYPROSINE KINASE, KINASE INHIBITOR, 7-AZAINDOLE, Alternative splicing, ATP-binding, Host-virus interaction, Kinase, Nucleotide-binding, Phosphoprotein, Polymorphism, SH2 domain, Transferase, Tyrosine-protein kinase, Ubl conjugation | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.26 Å ) | ||||||||||||
Citation : |
Structural insights for design of potent spleen tyrosine kinase inhibitors from crystallographic analysis of three inhibitor complexes.
Villasenor, A.G.,Kondru, R.,Ho, H.
et al.
PubMed: 19220318 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | P43405 (KSYK_HUMAN) | ||||||||
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