PDB ID: 3FLY
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Structure summary
Code : | 3FLY PDBj RCSB PDB PDBe | ||||||||||||
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Header : | SIGNALING PROTEIN, TRANSFERASE | ||||||||||||
Title : | P38 kinase crystal structure in complex with 6-(2,4-difluoro-phenoxy)-2-isopropylamino-8-methyl-8h-pyrido[2,3-D]pyrimidin-7-one | ||||||||||||
Release Data : | 2009-12-22 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kuglstatter, A., Ghate, M. | ||||||||||||
Keywords : | P38; MAP KINASE; SERINE/THREONINE KINASE, Alternative splicing, ATP-binding, Cytoplasm, Kinase, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase, Transferase, SIGNALING PROTEIN | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.80 Å ) | ||||||||||||
Citation : |
The Discovery of Pamapimod, R1503 and R1487 as Orally Bioavailable and Highly Selective Inhibitors of p38 Map Kinase
Soth, M.,Kuglstatter, A.,Goldstein, D.
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Reaction
Chain : | A | |||||||||||||
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UniProt : | Q16539 (MK14_HUMAN) | |||||||||||||
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