PDB ID: 3FJL
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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ACY | Acetic acid | PoSSuM | |||
CJH | (2z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide | PoSSuM | |||
FMN | Flavin mononucleotide | PoSSuM | |||
ORO | Orotic acid | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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Download interaction data: 3FJL
Structure summary
Code : | 3FJL PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 3 | ||||||||||||
Release Data : | 2009-06-09 | ||||||||||||
Compound : |
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Source : |
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Authors : | Heikkila, T. | ||||||||||||
Keywords : | Alpha-Beta Barrel, TIM Barrel, FAD, Flavoprotein, Membrane, Mitochondrion, Mitochondrion inner membrane, Oxidoreductase, Polymorphism, Pyrimidine biosynthesis, Transit peptide | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.90 Å ) | ||||||||||||
Citation : |
Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases
Davies, M.,Heikkila, T.,McConkey, G.A.
et al.
PubMed: 19351152 |
Reaction
Chain : | A | ||||||||
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UniProt : | Q02127 (PYRD_HUMAN) | ||||||||
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