PDB ID: 3FCF
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
FCF | 3-[(1e,7e)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid | PoSSuM | |||
SCN | Thiocyanate ion | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|
Code | Name | Show |
---|
Download interaction data: 3FCF
Structure summary
Code : | 3FCF PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | HYDROLASE | ||||||||||||
Title : | Complex of UNG2 and a fragment-based designed inhibitor | ||||||||||||
Release Data : | 2009-04-28 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Bianchet, M.A., Chung, S., Parker, J.B., Amzel, L.M., Stivers, J.T. | ||||||||||||
Keywords : | DNA REPAIR, URACIL, URACIL DNA GLYCOSYLASE, Alternative splicing, Disease mutation, DNA damage, Glycosidase, Host-virus interaction, Hydrolase, Mitochondrion, Nucleus, Phosphoprotein, Transit peptide | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.840 Å ) | ||||||||||||
Citation : |
Impact of linker strain and flexibility in the design of a fragment-based inhibitor
Chung, S.,Parker, J.B.,Bianchet, M.
et al.
PubMed: 19396178 Uracil-directed ligand tethering: an efficient strategy for uracil DNA glycosylase (UNG) inhibitor development
Jiang, T.L.,Krosky, D.J.,Seiple, L.
et al.
Mimicking damaged DNA with a small molecule inhibitor of human UNG2.
Krosky, D.J.,Bianchet, M.A.,Seiple, L.
et al.
|
Reaction
Chain : | A | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | P13051 (UNG_HUMAN) | ||||||||
|