Brand  (β version)

PDB ID: 3F3Z

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Ligands
Code Name Style Show Link
DRK 3-({[(3s)-3,4-dihydroxybutyl]oxy}amino)-1h,2'H-2,3'-biindol-2'-one PoSSuM
GOL Glycerol PoSSuM
Non-standard Residues
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SEP Phosphoserine
Glycosylation
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Structure summary

Code : 3F3Z   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE, KINASE
Title : Crystal structure of Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 in presence of indirubin E804
Release Data : 2008-12-23
Compound :
mol_id molecule chains
1 Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands A
Source :
mol_id organism_scientific expression_system
1 Cryptosporidium parvum Iowa II  (taxid:353152) Escherichia coli  (taxid:562)
gene: cgd7_1840
expression_system_strain: dh5a
expression_system_vector_type: plasmid
expression_system_plasmid: p15-mhl
Authors : Wernimont, A.K., Lew, J., Wasney, G., Kozieradzki, I., Cossar, D., Vedadi, M., Bochkarev, A., Arrowsmith, C.H., Sundstrom, M., Weigelt, J., Edwards, A.M., Hui, R., Artz, J.D., Amani, M., Structural Genomics Consortium (SGC)
Keywords : calcium dependent protein kinase, structural genomics consortium, ATP-binding, Kinase, Nucleotide-binding, Serine/threonine-protein kinase, Transferase, SGC
Exp. method : X-RAY DIFFRACTION ( 1.84 Å )
Citation :

Crystal structure of Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 in presence of indirubin E804

Wernimont, A.K.,Lew, J.,Wasney, G.  et al.
To be Published 

Reaction

Chain : A
UniProt : Q5CYL9 (Q5CYL9_CRYPI)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.1 ARBA:ARBA00001433
-
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.1 ARBA:ARBA00000775
-