PDB ID: 3CQU
Hetero Atom Contents
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Structure summary
Code : | 3CQU PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSFERASE | ||||||||||||||||||||||||
Title : | Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor | ||||||||||||||||||||||||
Release Data : | 2008-05-27 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Pandit, J. | ||||||||||||||||||||||||
Keywords : | Kinase, Apoptosis, ATP-binding, Carbohydrate metabolism, Cytoplasm, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Membrane, Nucleotide-binding, Nucleus, Phosphoprotein, Serine/threonine-protein kinase, Sugar transport, Transferase, Translation regulation, Transport, Alternative splicing, Wnt signaling pathway | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.200 Å ) | ||||||||||||||||||||||||
Citation : |
Synthesis and structure based optimization of novel Akt inhibitors
Lippa, B.,Pan, G.,Corbett, M.
et al.
PubMed: 18456494 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | P31749 (AKT1_HUMAN) | ||||||||||||
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Chain : | C | ||||||||||||||||||||
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UniProt : | P49841 (GSK3B_HUMAN) | ||||||||||||||||||||
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