PDB ID: 3C1X
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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CKK | N-{[4-({5-[(4-aminopiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}oxy)-3-fluorophenyl]carbamoyl}-2-(4-fluorophenyl)acetamide | PoSSuM |
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Download interaction data: 3C1X
Structure summary
Code : | 3C1X PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with a Pyrrolotriazine based inhibitor | ||||||||||||
Release Data : | 2008-03-18 | ||||||||||||
Compound : |
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Source : |
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Authors : | Sack, J. | ||||||||||||
Keywords : | RECEPTOR TYROSINE KINASE, SIGNAL TRANSDUCTION, GRB2, SHC, ATP-binding, Glycoprotein, Membrane, Nucleotide-binding, Phosphoprotein, Proto-oncogene, Transferase, Transmembrane, Tyrosine-protein kinase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.17 Å ) | ||||||||||||
Citation : |
Identification of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of Met kinase.
Schroeder, G.M.,Chen, X.T.,Williams, D.K.
et al.
PubMed: 18289854 |
Reaction
Chain : | A | ||||||||
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UniProt : | P08581 (MET_HUMAN) | ||||||||
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