PDB ID: 3BXR
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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DRR | (9s,12s)-9-(1-methylethyl)-N-[(8s,11s)-8-[(1s)-1-methylpropyl]-7,10-dioxo-2-oxa-6,9-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien-11-yl]-7,10-dioxo-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-1(16),14,17-triene-12-carboxamide | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
Code | Name | Show |
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ABA | Alpha-aminobutyric acid |
Code | Name | Emphasize |
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Download interaction data: 3BXR
Structure summary
Code : | 3BXR PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal Structures Of Highly Constrained Substrate And Hydrolysis Products Bound To HIV-1 Protease. Implications For Catalytic Mechanism | ||||||||||||
Release Data : | 2008-03-25 | ||||||||||||
Compound : |
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Authors : | Tyndall, J.D., Pattenden, L.K., Reid, R.C., Hu, S.H., Alewood, D., Alewood, P.F., Walsh, T., Fairlie, D.P., Martin, J.L. | ||||||||||||
Keywords : | HIV protease, HIVPR, substrate, product, AIDS, Aspartyl protease, Capsid maturation, Core protein, Cytoplasm, DNA integration, DNA recombination, DNA-directed DNA polymerase, Endonuclease, Hydrolase, Lipoprotein, Magnesium, Membrane, Metal-binding, Multifunctional enzyme, Myristate, Nuclease, Nucleotidyltransferase, Nucleus, Phosphoprotein, RNA-binding, RNA-directed DNA polymerase, Transferase, Viral nucleoprotein, Virion, Zinc, Zinc-finger | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.600 Å ) | ||||||||||||
Citation : |
Crystal Structures of Highly Constrained Substrate and Hydrolysis Products Bound to HIV-1 Protease. Implications for the Catalytic Mechanism
Tyndall, J.D.,Pattenden, L.K.,Reid, R.C.
et al.
PubMed: 18311928 Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease
Martin, J.L.,Begun, J.,Schindeler, A.
et al.
PubMed: 10387041 |
Reaction
Chain : | A, B | ||||||||||||||||||||||||
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UniProt : | P03369 (POL_HV1A2) | ||||||||||||||||||||||||
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