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Ligands
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FMZ (2r,4s)-5,5-dimethyl-2-[(1r)-2-oxo-1-({(2r)-2-[(2-oxoimidazolidin-1-yl)amino]-2-phenylacetyl}amino)ethyl]-1,3-thiazolidine-4-carboxylic acid
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Code : 3A3F   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)
Release Data : 2009-12-22
Compound :
mol_id molecule chains synonym
1 Penicillin-binding protein 4 A,B PBP4
ec: 3.4.16.4
fragment: UNP residues 28-479
Source :
mol_id organism_scientific expression_system
1 Haemophilus influenzae  (taxid:727) Escherichia coli  (taxid:562)
gene: dacB
expression_system_strain: BL21(DE3) star/pLysS
expression_system_vector_type: PLASMID
expression_system_plasmid: pET28b
Authors : Kawai, F., Roper, D.I., Park, S.-Y., Tame, J.R.H.
Keywords : Penicillin Binding Protein 4, PBP4, dacB, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.10 Å )
Citation :

Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae

Kawai, F.,Clarke, T.B.,Roper, D.I.  et al.
(2010)  J.Mol.Biol.  396 : 634 - 645

PubMed: 19958776
DOI: 10.1016/j.jmb.2009.11.055

Chain : A, B
UniProt : A8E0K8 (A8E0K8_HAEIF)
Reaction : -