Brand  (β version)

PDB ID: 3VVA

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Ligands
Code Name Style Show Link
FE Fe (III) ion PoSSuM
OH Hydroxide ion PoSSuM
CHW 3-chloro-4,6-dihydroxy-5-[(2e,6e,8s)-8-hydroxy-3,7-dimethylnona-2,6-dien-1-yl]-2-methylbenzaldehyde PoSSuM
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Structure summary

Code : 3VVA   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Title : Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative
Release Data : 2013-03-13
Compound :
mol_id molecule chains
1 Alternative oxidase, mitochondrial A,B,C,D
Source :
mol_id organism_scientific expression_system
1 Trypanosoma brucei brucei  (taxid:5702) ESCHERICHIA COLI  (taxid:562)
gene: AOX
expression_system_strain: FN102
expression_system_vector_type: PLASMID
expression_system_plasmid: PET15B
Authors : Shiba, T., Kido, Y., Sakamoto, K., Inaoka, D.K., Tsuge, C., Tatsumi, R., Balogun, E.O., Nara, T., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Saimoto, H., Moore, A.L., Harada, S., Kita, K.
Keywords : HELIX DOUBLE, MEMBRANE BOUND DIIRON PROTEIN, OXIDASE, MEMBRANE, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX, ALTERNATIVE OXIDASE
Exp. method : X-RAY DIFFRACTION ( 2.59 Å )
Citation :

Structure of the trypanosome cyanide-insensitive alternative oxidase

Shiba, T.,Kido, Y.,Sakamoto, K.  et al.
(2013)  Proc.Natl.Acad.Sci.USA  110 : 4580 - 4585

PubMed: 23487766
DOI: 10.1073/pnas.1218386110

Reaction

Chain : A, B, C, D
UniProt : Q26710 (AOX_TRYBB)
Reaction : -