Brand  (β version)

PDB ID: 3VM6

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Ligands
Code Name Style Show Link
CL Chloride ion PoSSuM
MG Magnesium ion PoSSuM
PEG Di(hydroxyethyl)ether PoSSuM
PG4 Tetraethylene glycol PoSSuM
RI2 1,5-di-O-phosphono-alpha-D-ribofuranose PoSSuM
Non-standard Residues
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Structure summary

Code : 3VM6   PDBj   RCSB PDB   PDBe
Header : ISOMERASE
Title : Crystal structure of ribose-1,5-bisphosphate isomerase from Thermococcus kodakarensis KOD1 in complex with alpha-D-ribose-1,5-bisphosphate
Release Data : 2012-04-25
Compound :
mol_id molecule chains
1 Translation initiation factor eIF-2B, delta subunit A,B,C
ec: 5.3.1.-
mutation: C133S
Source :
mol_id organism_scientific expression_system
1 Thermococcus kodakarensis  (taxid:69014) Escherichia coli  (taxid:562)
strain: KOD1
gene: E2b2, TK0185
expression_system_strain: BL21-CodonPlus(DE3)-RIL-X
expression_system_vector_type: PLASMID
expression_system_plasmid: pCold I
Authors : Nakamura, A., Fujihashi, M., Aono, R., Sato, T., Nishiba, Y., Yoshida, S., Yano, A., Atomi, H., Imanaka, T., Miki, K.
Keywords : ROSSMANN FOLD, HEXAMER, ISOMERASE, AMP METABOLISM, SUGAR BINDING
Exp. method : X-RAY DIFFRACTION ( 2.85 Å )
Citation :

Dynamic, ligand-dependent conformational change triggers reaction of ribose-1,5-bisphosphate isomerase from Thermococcus kodakarensis KOD1

Nakamura, A.,Fujihashi, M.,Aono, R.  et al.
(2012)  J.Biol.Chem.  287 : 20784 - 20796

PubMed: 22511789
DOI: 10.1074/jbc.M112.349423

Reaction

Chain : A, B, C
UniProt : Q5JFM9 (R15PI_THEKO)
Reaction: EC: Evidence:
Physiological Direction:
alpha-D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate 5.3.1.29 HAMAP-Rule:MF_02230, PubMed:17303759, PubMed:22511789, PubMed:23065974
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