Brand  (β version)

PDB ID: 3V8E

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Ligands
Code Name Style Show Link
ZN Zinc ion PoSSuM
MG Magnesium ion PoSSuM
Non-standard Residues
Code Name Show
JJJ S-(pyridin-3-ylcarbonyl)-L-cysteine
Glycosylation
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Structure summary

Code : 3V8E   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of the yeast nicotinamidase Pnc1p bound to the inhibitor nicotinaldehyde
Release Data : 2012-01-25
Compound :
mol_id molecule chains synonym
1 Nicotinamidase A,B,C,D,E,F,G Nicotine deamidase, NAMase
ec: 3.5.1.19
Source :
mol_id organism_scientific organism_common expression_system
1 Saccharomyces cerevisiae  (taxid:559292) Baker's yeast Escherichia coli  (taxid:562)
strain: ATCC 204508 / S288c
gene: PNC1, YGL037C
Authors : Hoadley, K.A., Smith, B.C., Denu, J.M., Keck, J.L.
Keywords : Hydrolase
Exp. method : X-RAY DIFFRACTION ( 2.71 Å )
Citation :

Structural and Kinetic Isotope Effect Studies of Nicotinamidase (Pnc1) from Saccharomyces cerevisiae.

Smith, B.C.,Anderson, M.A.,Hoadley, K.A.  et al.
(2012)  Biochemistry  51 : 243 - 256

PubMed: 22229411
DOI: 10.1021/bi2015508

Reaction

Chain : A, B, C, D, E, F, G
UniProt : P53184 (PNC1_YEAST)
Reaction: EC: Evidence:
Physiological Direction:
H2O + nicotinamide = NH4(+) + nicotinate 3.5.1.19 PubMed:17382284
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