Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

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Ligands
Code Name Link
0LH 2-(1h-indol-1-yl)ethanamine
Code : 3V1S
Header : LYASE
Title : Scaffold tailoring by a newly detected Pictet-Spenglerase ac-tivity of strictosidine synthase (STR1): from the common tryp-toline skeleton to the rare piperazino-indole framework
Release Data : 2012-02-29
Compound :
mol_id molecule chains
1 Strictosidine synthase A,B
ec: 4.3.3.2
Source :
mol_id organism_scientific organism_common expression_system
1 Rauvolfia serpentina  (taxid:4060) Devilpepper Escherichia coli  (taxid:562)
gene: STR1
expression_system_vector_type: plasmid
Authors : Wu, F., Zhu, H., Sun, L., Rajendran, C., Wang, M., Ren, X., Panjikar, S., Cherkasov, A., Zou, H., Stoeckigt, J.
Keywords : Strictosidine synthase, Alkaloid biosynthesis, Strictosidine synthase family, LYASE
Exp. method : X-RAY DIFFRACTION ( 2.3280 Å )
Citation :

Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework

Wu, F.,Zhu, H.,Sun, L.  et al.
(2012)  J.Am.Chem.Soc.  134 : 1498 - 1500

PubMed: 22229634
DOI: 10.1021/ja211524d

Chain : A, B
UniProt : P68175 (STSY_RAUSE)
Reaction : 3-alpha-(S)-strictosidine + H(2)O = tryptamine + secologanin.