Brand  (β version)

PDB ID: 3V0W

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Ligands
Code Name Style Show Link
SO4 Sulfate ion PoSSuM
GLA Alpha-D-galactopyranose PoSSuM
GLC Alpha-D-glucopyranose PoSSuM
GM0 4-O-phosphono-L-glycero-alpha-D-manno-heptopyranose PoSSuM
GMH L-glycero-alpha-D-manno-heptopyranose PoSSuM
KDO 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid PoSSuM
PA1 2-amino-2-deoxy-alpha-D-glucopyranose PoSSuM
: Polysaccharide
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Structure summary

Code : 3V0W   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Crystal structure of Fab WN1 222-5 in complex with LPS
Release Data : 2012-12-05
Compound :
mol_id molecule chains
1 WN1 222-5 Fab (IgG2a) light chain L
mol_id molecule chains
2 WN1 222-5 Fab (IgG2a) heavy chain H
Source :
mol_id organism_scientific organism_common
1 Mus musculus  (taxid:10090) Mouse
strain: NZB
cell: HYBRIDOMA
mol_id organism_scientific organism_common
2 Mus musculus  (taxid:10090) Mouse
strain: NZB
cell: HYBRIDOMA
Authors : Gomery, K., Evans, S.V.
Keywords : Beta barrel, Antibody, Fab, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 1.73 Å )
Citation :

Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS.

Gomery, K.,Muller-Loennies, S.,Brooks, C.L.  et al.
(2012)  Proc.Natl.Acad.Sci.USA  109 : 20877 - 20882

PubMed: 23184990
DOI: 10.1073/pnas.1209253109