Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
0CK 4-[1-cyclohexyl-4-(4-fluorophenyl)-1h-imidazol-5-yl]pyrimidin-2-amine
Code : 3UZP
Header : TRANSFERASE/TRANSFERASE INHIBITOR
Title : crystal structure of ck1d with PF670462 from P21 crystal form
Release Data : 2012-01-11
Compound :
mol_id molecule chains synonym
1 Casein kinase I isoform delta A,B CKI-delta, CKId
ec: 2.7.11.1
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
gene: CSNK1D
Authors : Huang, X.
Keywords : ck1d, kinase, inhibitor, PF670462, TRANSFERASE-TRANSFERASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.94 Å )
Citation :

Structural basis for the interaction between casein kinase 1 delta and a potent and selective inhibitor.

Long, A.,Zhao, H.,Huang, X.
(2012)  J.Med.Chem.  55 : 956 - 960

PubMed: 22168824
DOI: 10.1021/jm201387s

Chain : A, B
UniProt : P48730 (KC1D_HUMAN)
Reaction : ATP + a protein = ADP + a phosphoprotein.
ATP + [tau protein] = ADP + [tau protein] phosphate.