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Ligands
Code Name Style Show Link
0CU 5,7-dichloro-1h-benzotriazole
PO4 Phosphate ion
NA Sodium ion
Non-standard Residues
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Code : 3UZ5   PDBj   RCSB PDB   PDBe
Header : LYASE/LYASE INHIBITOR
Title : Designed protein KE59 R13 3/11H
Release Data : 2012-06-06
Compound :
mol_id molecule chains
1 Kemp eliminase KE59 R13 3/11H A,B
ec: 4.-.-.-
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli  (taxid:562)
Authors : Khersonsky, O., Kiss, G., Roethlisberger, D., Dym, O., Albeck, S., Houk, K.N., Baker, D., Tawfik, D.S., Israel Structural Proteomics Center (ISPC)
Keywords : Structural Genomics, Israel Structural Proteomics Center, ISPC, Beta Barrel, LYASE-LYASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59.

Khersonsky, O.,Kiss, G.,Rothlisberger, D.  et al.
(2012)  Proc.Natl.Acad.Sci.USA  109 : 10358 - 10363

PubMed: 22685214
DOI: 10.1073/pnas.1121063109