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Ligands
Code Name Style Show Link
0DV (4r,5r,6r,6as,9s,9ae,10ar)-5-hydroxy-9-(hydroxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,D][8]annulen-4-yl alpha-D-gulopyranoside
CL Chloride ion
GOL Glycerol
MG Magnesium ion
Non-standard Residues
Code Name Show
CSO S-hydroxycysteine
SEP Phosphoserine
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 3UX0   PDBj   RCSB PDB   PDBe
Header : PEPTIDE BINDING PROTEIN
Title : Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer Fusicoccin H
Release Data : 2013-01-02
Compound :
mol_id molecule chains synonym
1 14-3-3 protein sigma A Epithelial cell marker protein 1, Stratifin
mol_id molecule chains
2 TASK3 PHOSPHOPEPTIDE P
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:469008)
gene: HME1, SFN
expression_system_strain: ROSETTA DE3
expression_system_vector_type: PLASMID
expression_system_plasmid: PPROEX HTB
mol_id organism_scientific
2 Homo sapiens  (taxid:9606)
synthetic: yes
other_details: This sequence occurs naturally in humans.
Authors : Thiel, P., Bartel, M., Anders, C., Higuchi, Y., Schumacher, B., Kato, N., Ottmann, C.
Keywords : Helical protein, Phosphoprotein, Adapter protein, Peptide binding protein, Nucleus
Exp. method : X-RAY DIFFRACTION ( 1.7500 Å )
Citation :

A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of k(+) channels at the cell surface.

Anders, C.,Higuchi, Y.,Koschinsky, K.  et al.
(2013)  Chem.Biol.  20 : 583 - 593

PubMed: 23601647
DOI: 10.1016/j.chembiol.2013.03.015

Chain : A
UniProt : P31947 (1433S_HUMAN)
Reaction : -
Chain : P
UniProt : Q9NPC2 (KCNK9_HUMAN)
Reaction : -