Brand  (β version)

PDB ID: 3UJN

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Ligands
Code Name Style Show Link
ADP Adenosine-5'-diphosphate PoSSuM
MG Magnesium ion PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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CYG 2-amino-4-(amino-3-oxo-propylsulfanylcarbonyl)-butyric acid
Glycosylation
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Structure summary

Code : 3UJN   PDBj   RCSB PDB   PDBe
Header : LIGASE
Title : Formyl Glycinamide Ribonucleotide Amidotransferase from Salmonella Typhimurium : Role of the ATP complexation and glutaminase domain in catalytic coupling
Release Data : 2012-06-06
Compound :
mol_id molecule chains synonym
1 Phosphoribosylformylglycinamidine synthase A FGAM synthase, FGAMS, Formylglycinamide ribotide amidotransferase, FGARAT, Formylglycinamide ribotide synthetase
ec: 6.3.5.3
Source :
mol_id organism_scientific
1 Salmonella enterica subsp. enterica serovar Typhimurium  (taxid:90371)
Authors : Anand, R., Morar, M., Tanwar, A.S., Panjikar, S.
Keywords : Amidotransferase, Glutaminase, LIGASE
Exp. method : X-RAY DIFFRACTION ( 2.98 Å )
Citation :

Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling

Tanwar, A.S.,Morar, M.,Panjikar, S.  et al.
(2012)  Acta Crystallogr.,Sect.D  68 : 627 - 636

PubMed: 22683785
DOI: 10.1107/S0907444912006543

Reaction

Chain : A
UniProt : P74881 (PUR4_SALTY)
Reaction: EC: Evidence:
Physiological Direction:
N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + L- glutamine + ATP + H2O = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + L-glutamate + ADP + phosphate + H(+) 6.3.5.3 HAMAP-Rule:MF_00419
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