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Ligands
Code Name Style Show Link
09V Cyclopropylmethanol
PO4 Phosphate ion
ZN Zinc ion
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Glycosylation
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Code : 3UGL   PDBj   RCSB PDB   PDBe
Header : METAL BINDING PROTEIN
Title : Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
Release Data : 2012-12-12
Compound :
mol_id molecule chains synonym
1 Proteine kinase C delta type A,B nPKC-delta
ec: 2.7.11.13
fragment: C1B Subdomain of PKC delta, UNP residues 231-280
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) Mouse Escherichia coli  (taxid:562)
gene: Prkcd, Pkcd
Authors : Shanmugasundararaj, S., Stehle, T., Miller, K.W.
Keywords : Proteine kinase C delta, PHOSPHOTRANSFERASE, Anesthetic binding site, METAL BINDING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.357 Å )
Citation :

Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta

Shanmugasundararaj, S.,Das, J.,Sandberg, W.S.  et al.
(2012)  Biophys.J.  103 : 2331 - 2340

PubMed: 23283232
DOI: 10.1016/j.bpj.2012.10.034

Crystal structure of the cys2 activator binding domain of protein kinase C delta in complex with phorbol ester

Zhang, G.,Kazanietz, M.G.,Blumberg, P.M.  et al.
(1995)  Cell(Cambridge,Mass.)  81 : 917 - 924

Chain : A, B
UniProt : P28867 (KPCD_MOUSE)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.13 -
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ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.13 PubMed:22265677
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ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl- [protein] 2.7.10.2 PROSITE-ProRule:PRU10027
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