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Ligands
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09N (11z,14z)-N-[(2s,3s,4r)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide
Non-standard Residues
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Glycosylation
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NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Code : 3UBX   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Crystal structure of the mouse CD1d-C20:2-aGalCer-L363 mAb Fab complex
Release Data : 2011-11-16
Compound :
mol_id molecule chains synonym
1 Antigen-presenting glycoprotein CD1d1 A,D T cell surface glycoprotein CD1d
fragment: UNP residues 19-297
mol_id molecule chains
2 Beta-2-microglobulin B,E
fragment: UNP residues 21-119
mol_id molecule chains
3 L363 light chain (IGKV13-84*01) L,I
fragment: Fab
mol_id molecule chains
4 L363 heavy chain (IGHV9-4*02) H,G
fragment: Fab
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) Mouse Spodoptera frugiperda  (taxid:7108)
gene: Cd1.1, CD1d, Cd1d1
expression_system_common: Fall armyworm
expression_system_strain: Sf9
expression_system_vector_type: baculovirus
expression_system_plasmid: pBACp10pH
mol_id organism_scientific organism_common expression_system
2 Mus musculus  (taxid:10090) Mouse Spodoptera frugiperda  (taxid:7108)
gene: B2m, CD1d
expression_system_common: Fall armyworm
expression_system_strain: Sf9
expression_system_vector_type: baculovirus
expression_system_plasmid: pBACp10pH
mol_id organism_scientific organism_common
3 Mus musculus  (taxid:10090) Mouse
strain: BALB/c
mol_id organism_scientific organism_common
4 Mus musculus  (taxid:10090) Mouse
strain: BALB/c
Authors : Yu, E.D., Zajonc, D.M.
Keywords : Immunology, mouse CD1d/NKT, mAb, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 3.10 Å )
Citation :

Structural basis for the recognition of C20:2-alpha GalCer by the invariant natural killer T cell receptor-like antibody L363.

Yu, E.D.,Girardi, E.,Wang, J.  et al.
(2012)  J.Biol.Chem.  287 : 1269 - 1278

PubMed: 22110136
DOI: 10.1074/jbc.M111.308783

Chain : A, D
UniProt : P11609 (CD1D1_MOUSE)
Reaction : -
Chain : B, E
UniProt : P01887 (B2MG_MOUSE)
Reaction : -