Brand  (β version)

color scheme of protein:


interaction residue:

chain: Hide other chain(s)

Code Name Link
09Q 1-(5-phenylpyridin-3-yl)-1,4-diazepane
SO4 Sulfate ion
Code : 3U8L
Header : Acetylcholine-binding protein/agonist
Title : Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3570 (1-(5-phenylpyridin-3-yl)-1,4-diazepane)
Release Data : 2011-12-14
Compound :
mol_id molecule chains synonym
1 Acetylcholine-binding protein A,B,C,D,E,F,G,H,I,J ACh-binding protein, AchBP
Source :
mol_id organism_scientific organism_common expression_system
1 Lymnaea stagnalis  (taxid:6523) Great pond snail Spodoptera frugiperda  (taxid:7108)
expression_system_strain: Sf9
expression_system_vector_type: pFastbac I
Authors : Rohde, L.A.H., Ahring, P.K., Jensen, M.L., Nielsen, E.O., Peters, D., Helgstrand, C., Krintel, C., Harpsoe, K., Gajhede, M., Kastrup, J.S., Balle, T.
Keywords : Lymnaea stagnalis, agonist, Ligand-bindig domain, Acetylcholine, Acetylcholine-binding protein, Acetylcholine-binding protein-agonist complex
Exp. method : X-RAY DIFFRACTION ( 2.320 Å )
Citation :

Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha 4 beta 2 receptors: unique role of halogen bonding revealed.

Rohde, L.A.,Ahring, P.K.,Jensen, M.L.  et al.
(2012)  J.Biol.Chem.  287 : 4248 - 4259

PubMed: 22170047
DOI: 10.1074/jbc.M111.292243

Chain : A, B, C, D, E, F, G, H, I, J
UniProt : P58154 (ACHP_LYMST)
Reaction : -