PDB ID: 3U15
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Structure summary
Code : | 3U15 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | PROTEIN BINDING | ||||||||||||
Title : | Structure of hDMX with Dimer Inducing Indolyl Hydantoin RO-2443 | ||||||||||||
Release Data : | 2012-06-27 | ||||||||||||
Compound : |
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Source : |
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Authors : | Lukacs, C.M., Janson, C.A., Graves, B.J. | ||||||||||||
Keywords : | cell cycle, ubiquitin ligase, MDM2, MDMX, p53, PROTEIN BINDING | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.80 Å ) | ||||||||||||
Citation : |
Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.
Graves, B.,Thompson, T.,Xia, M.
et al.
PubMed: 22745160 |
Reaction
Chain : | A, B, C, D |
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UniProt : | O15151 (MDM4_HUMAN) |
Reaction : | - |