Brand  (β version)

PDB ID: 3TY0

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Ligands
Code Name Style Show Link
082 (5r)-5-(3-{[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-2,3-dihydro-1h-benzimidazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione PoSSuM
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Structure summary

Code : 3TY0   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION REGULATOR
Title : Structure of PPARgamma ligand binding domain in complex with (R)-5-(3-((3-(6-methoxybenzo[D]isoxazol-3-yl)-2-oxo-2,3-dihydro-1H-benzo[D]imidazol-1-yl)methyl)phenyl)-5-methyloxazolidine-2,4-dione
Release Data : 2011-11-23
Compound :
mol_id molecule chains synonym
1 Peroxisome proliferator-activated receptor gamma A,B PPAR-gamma, Nuclear receptor subfamily 1 group C member 3
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
gene: PPARG, NR1C3
Authors : Soisson, S.M., Meinke, P.M., McKeever, B., Liu, W.
Keywords : nuclear receptor ligand binding domain, TRANSCRIPTION REGULATOR
Exp. method : X-RAY DIFFRACTION ( 2.0000 Å )
Citation :

Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) modulators.

Liu, W.,Lau, F.,Liu, K.  et al.
(2011)  J.Med.Chem.  54 : 8541 - 8554

PubMed: 22070604
DOI: 10.1021/jm201061j

Reaction

Chain : A, B
UniProt : P37231 (PPARG_HUMAN)
Reaction : -