Het-PDB Navi2 (PDB: 3TVM)

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Ligands
Code	Name		Style	Show	Link
07P	N-[(2s,3r)-10-[(1r,2r)-2-decylcyclopropyl]-1-(alpha-D-galactopyranosyloxy)-3-hydroxydecan-2-yl]hexacosanamide				PoSSuM
CL	Chloride ion				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose
FUC	Alpha-L-fucopyranose

Modification
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Download interaction data: 3TVM

Code :

3TVM PDBj RCSB PDB PDBe

Header :

IMMUNE SYSTEM

Title :

Structure of the mouse CD1d-SMC124-iNKT TCR complex

Release Data :

2012-02-01

Compound :

mol_id	molecule	chains	synonym
1	Antigen-presenting glycoprotein CD1d1	A,E	T cell surface glycoprotein CD1d
	fragment: residues 19-298

mol_id	molecule	chains
2	beta-2-microglobulin	B,F

mol_id	molecule	chains
3	Valpha14 (mouse variable domain, human constant domain)	C,G

mol_id	molecule	chains
4	Vbeta8.2 (mouse variable domain, human constant domain)	D,H

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Mus musculus (taxid:10090)	Mouse	Spodoptera frugiperda (taxid:7108)
	gene: Cd1.1, CD1d, Cd1d1 expression_system_common: Fall armyworm expression_system_cell_line: Sf9 expression_system_vector_type: baculovirus transfer vector expression_system_plasmid: pBACp10pH

mol_id	organism_scientific	organism_common	expression_system
2	Mus musculus (taxid:10090)	Mouse	Spodoptera frugiperda (taxid:7111)
	gene: beta-2-microglobulin expression_system_common: Fall armyworm expression_system_cell_line: Sf9 expression_system_vector_type: baculovirus transfer vector expression_system_plasmid: pBACp10pH

mol_id	organism_scientific	expression_system
3	Mus musculus, Homo sapiens (taxid:10090, 9606)	Escherichia coli (taxid:469008)
	gene: Valpha14 (mouse variable domain, human constant domain) expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET22b

mol_id	organism_scientific	expression_system
4	Mus musculus, Homo sapiens (taxid:10090, 9606)	Escherichia coli (taxid:469008)
	gene: Vbeta8.2 (mouse variable domain, human constant domain) expression_system_strain: BL21DE3 expression_system_vector_type: plasmid expression_system_plasmid: pET30a

Authors :

Girardi, E., Li, Y., Zajonc, D.M.

Keywords :

antigen presentation, glycolipid, NKT cells, IMMUNE SYSTEM

Exp. method :

X-RAY DIFFRACTION ( 2.80 Å )

Citation :

Glycolipids that Elicit IFN-gama-Biased Responses from Natural Killer T Cells

Tyznik, A.J.,Farber, E.,Girardi, E. et al.
(2011) Chem.Biol. 18 : 1620 - 1630

PDB ID: 3TVM