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Ligands
Code Name Style Show Link
CTN 4-amino-1-beta-D-ribofuranosyl-2(1h)-pyrimidinone
PG4 Tetraethylene glycol
SAM S-adenosylmethionine
SO4 Sulfate ion
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Code : 3TKA   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : crystal structure and solution saxs of methyltransferase rsmh from E.coli
Release Data : 2012-05-30
Compound :
mol_id molecule chains synonym
1 Ribosomal RNA small subunit methyltransferase H A 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH
ec: 2.1.1.199
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:83333) Escherichia coli  (taxid:562)
strain: K-12
gene: rsmH, mraW, yabC, b0082, JW0080
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28a
Authors : Gao, Z.Q., Wei, Y., Zhang, H., Dong, Y.H.
Keywords : methyl transferase, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.250 Å )
Citation :

Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.

Wei, Y.,Zhang, H.,Gao, Z.Q.  et al.
(2012)  J.Struct.Biol.  179 : 29 - 40

PubMed: 22561317
DOI: 10.1016/j.jsb.2012.04.011

Chain : A
UniProt : P60390 (RSMH_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine 2.1.1.199 PubMed:19965768
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