Het-PDB Navi2 (PDB: 3T9V)

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Ligands
Code	Name		Style	Show	Link
CNI	7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile				PoSSuM
ZN	Zinc ion				PoSSuM

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Download interaction data: 3T9V

Code :

3T9V PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

CNQX bound to a reduced double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2

Release Data :

2011-08-17

Compound :

mol_id	molecule	chains	synonym
1	Glutamate receptor 2	A,B	GluA2, GluR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2
	fragment: SEE REMARK 999 mutation: A473C/S673C

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Rattus norvegicus (taxid:10116)	Rat	Escherichia coli (taxid:562)
	gene: Gria2,GluA2 expression_system_strain: Origami B (DE3) expression_system_vector_type: PLASMID expression_system_plasmid: pET-22b(+)

Authors :

Ahmed, A.H., Oswald, R.E.

Keywords :

S1S2, neurotransmitter receptor, TRANSPORT PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.975 Å )

Citation :

Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS.

Ahmed, A.H.,Wang, S.,Chuang, H.H. et al.
(2011) J.Biol.Chem. 286 : 35257 - 35266

PDB ID: 3T9V