Brand  (β version)

PDB ID: 3T80

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Ligands
Code Name Style Show Link
ZN Zinc ion PoSSuM
MG Magnesium ion PoSSuM
CTN 4-amino-1-beta-D-ribofuranosyl-2(1h)-pyrimidinone PoSSuM
POP Pyrophosphate 2- PoSSuM
EDO 1,2-ethanediol PoSSuM
Non-standard Residues
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Structure summary

Code : 3T80   PDBj   RCSB PDB   PDBe
Header : LYASE
Title : Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine
Release Data : 2011-09-14
Compound :
mol_id molecule chains synonym
1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase A,B,C,D,E,F MECDP-synthase, MECPS
ec: 4.6.1.12
Source :
mol_id organism_scientific expression_system
1 Salmonella enterica subsp. enterica serovar Typhimurium  (taxid:90371) Escherichia coli  (taxid:469008)
strain: LT2
gene: ispF, STM2929
expression_system_strain: BL21(DE3)MAGIC
expression_system_vector_type: plasmid
expression_system_plasmid: PMCSG7
Authors : Seattle Structural Genomics Center for Infectious Disease (SSGCID), Staker, B.L., Edwards, T.E.
Keywords : IspF, Isoprenoid biosynthesis, SSGCID, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, Alpha Beta, LYASE
Exp. method : X-RAY DIFFRACTION ( 2.50 Å )
Citation :

Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine

Seattle Structural Genomics Center for Infectious Disease (SSGCID),Staker, B.L.,Edwards, T.E.
To be Published 

Reaction

Chain : A, B, C, D, E, F
UniProt : Q8ZMF7 (ISPF_SALTY)
Reaction: EC: Evidence:
Physiological Direction:
4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D- erythritol 2,4-cyclic diphosphate + CMP 4.6.1.12 HAMAP-Rule:MF_00107
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