Het-PDB Navi2 (PDB: 3T5I)

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Ligands
Code	Name		Style	Show	Link
FAR	Farnesyl				PoSSuM

Non-standard Residues
Code	Name	Show
CMT	O-methylcysteine

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 3T5I

Code :

3T5I PDBj RCSB PDB PDBe

Header :

LIPID BINDING PROTEIN

Title :

Structure of Fully modified farnesylated Rheb Peptide in complex with PDE6D

Release Data :

2011-11-02

Compound :

mol_id	molecule	chains	synonym
1	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	B,A,C,D	GMP-PDE delta, Protein p17
	fragment: Full length PDE delta

mol_id	molecule	chains
2	C-terminal Farnesylated Rheb peptide CSQQGKSS(CMT)	Q,R
	fragment: C-terminal Farnesylated Rheb peptide

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: PDE6D, PDED

mol_id	organism_scientific
2
	synthetic: yes other_details: Peptide synthesis , the sequence is the Cterminal sequence of Rheb

Authors :

Ismail, S.A., Chen, Y.-X., Wittinghofer, A.

Keywords :

Immunoglobulin-like beta sandwitch fold, Rheb, Farnesyl, prenyl, SIGNALING PROTEIN, LIPID BINDING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.10 Å )

Citation :

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo.

Ismail, S.A.,Chen, Y.X.,Rusinova, A. et al.
(2011) Nat.Chem.Biol. 7 : 942 - 949

PDB ID: 3T5I