Het-PDB Navi2 (PDB: 3SFY)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
3FX	(2r)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid	PoSSuM
3FY	N-(2-{(4-bromophenyl)[(1-methyl-1h-imidazol-5-yl)methyl]amino}ethyl)-1-methyl-N-(2-methylbenzyl)-1h-imidazole-4-sulfonamide	PoSSuM
FII	[(3,7,11-trimethyl-dodeca-2,6,10-trienyloxycarbamoyl)-methyl]-phosphonic acid	PoSSuM
SO4	Sulfate ion	PoSSuM
ZN	Zinc ion	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 3SFY

Code :

3SFY PDBj RCSB PDB PDBe

Header :

TRANSFERASE/TRANSFERASE INHIBITOR

Title :

Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and ethylenediamine inhibitor 2

Release Data :

2011-08-03

Compound :

mol_id	molecule	chains
1	Cryptococcus neoformans protein farnesyltransferase alpha subunit	A

mol_id	molecule	chains
2	Cryptococcus neoformans protein farnesyltransferase beta subunit	B

Source :

mol_id	organism_scientific	expression_system
1	Cryptococcus neoformans (taxid:235443)	Escherichia coli (taxid:562)
	strain: H99

mol_id	organism_scientific	expression_system
2	Cryptococcus neoformans (taxid:235443)	Escherichia coli (taxid:562)
	strain: H99

Authors :

Hast, M.A., Beese, L.S.

Keywords :

prenyltransferase, protein farnesyltransferase, TRANSFERASE-TRANSFERASE INHIBITOR complex

Exp. method :

X-RAY DIFFRACTION ( 2.10 Å )

Citation :

Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.

Hast, M.A.,Nichols, C.B.,Armstrong, S.M. et al.
(2011) J.Biol.Chem. 286 : 35149 - 35162

PDB ID: 3SFY