Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
F78 3-hydroxy-N-[(2s,3r)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](3-phenylpropyl)amino}-1-phenylbutan-2-yl]benzamide
PO4 Phosphate ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 3SAB   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Crystal structure of wild-type HIV-1 protease in complex with AF78
Release Data : 2012-06-06
Compound :
mol_id molecule chains
1 Protease A,B
mutation: Q7K
Source :
mol_id organism_scientific expression_system
1 Human immunodeficiency virus 1  (taxid:11676) Escherichia coli  (taxid:562)
strain: HXB2
gene: gag-pol, pol
expression_system_strain: TAP106
expression_system_vector_type: plasmid
expression_system_plasmid: pXC35
Authors : Schiffer, C.A., Nalam, M.N.L.
Keywords : HIV-1 protease, drug resistance, drug design, protease inhibitors, AIDS, aspartyl protease, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.50 Å )
Citation :

Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance

Altman, M.D.,Nalam, M.N.L.,Ali, A.  et al.
To be Published 

Chain : A, B
UniProt : O38732 (O38732_9HIV1)
Reaction : -