Het-PDB Navi2 (PDB: 3S4P)

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Ligands
Code	Name		Style	Show	Link
JS6	(1r,2r,3s,4r,6s)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(2-phenylethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside				PoSSuM

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Download interaction data: 3S4P

Code :

3S4P PDBj RCSB PDB PDBe

Header :

RNA/ANTIBIOTIC

Title :

Crystal structure of the bacterial ribosomal decoding site complexed with an amphiphilic paromomycin O2''-ether analogue

Release Data :

2011-09-21

Compound :

mol_id	molecule	chains
1	RNA (5'-R(PGPCPGPUPCPAPCPAPCPCPGPGPUPGPAPAPGPUPCPGP*C)-3')	A,B

Source :

mol_id	organism_scientific
1
	synthetic: yes other_details: Chemically synthesized

Authors :

Szychowski, J., Kondo, J., Zahr, O., Auclair, K., Westhof, E., Hanessian, S., Keillor, J.W.

Keywords :

aminoglycoside, antibiotics, ribosome, decoding site, RNA, RNA-ANTIBIOTIC complex

Exp. method :

X-RAY DIFFRACTION ( 2.5600 Å )

Citation :

Inhibition of aminoglycoside-deactivating enzymes APH(3')-IIIa and AAC(6')-Ii by amphiphilic paromomycin O2''-ether analogues

Szychowski, J.,Kondo, J.,Zahr, O. et al.
(2011) Chemmedchem 6 : 1961 - 1966

PDB ID: 3S4P